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IMBRUVICA has become the first FDA-approved therapy for these younger patients who previously had no approved treatment options for this life-threatening disease. Chronic graft vs. host condition can occur after a stem cell or bone marrow transplant when newly transplanted donor cells attack the transplant recipient’s body. Symptoms of the disease can include skin rashes, mouth sores, dry eyes, liver inflammation, the development of scar tissue in the skin and joints, and damage to the lungs. This milestone marks the first pediatric indication for the drug and the subsequent introduction of a new oral suspension formulation for patients aged under 12. The FDA-Approved drug can be sold in more than 100 countries and has been capable of treating more than 300,000 child patients worldwide
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