A biological sequence search uses specialized algorithms and databases to analyse DNA, RNA, or protein sequences, enabling the identification of similarities, conserved patterns, or potential functional relationships to support research, & IP protection. Whether you’re validating the novelty of a sequence, checking for potential overlaps, or exploring competitive landscapes, our expert-led process ensures accuracy and confidence at every step.
Ingenious e-Brain’s biological sequence search services are designed for researchers, biotech companies, law firms & inventors to strengthen their IP sequence search decisions. With clear insights, detailed reporting, and expert guidance, we help you identify the potential roadblocks and accelerate decision-making.
When our experts receive a sequence search request, the first step is determining whether the query should be searched against DNA, RNA, protein, or all relevant sequence types.
• The process begins by understanding the query sequence, including its length, type (DNA, RNA, protein/peptide, nucleic acids), and specific elements such as CDRs or motifs.
• We select the most appropriate databases to ensure comprehensive and relevant coverage.
• Suitable search parameters including percentage identity and e-value thresholds are then chosen based on the project requirements.
• We choose the appropriate scoring matrix, typically PAM30 or BLOSUM62, to ensure accurate alignment and meaningful results.
We conduct a comprehensive patent search across all relevant technical domains using a multi-layered strategy to ensure thorough coverage and accuracy.
• Keyword-based searching to capture variations in terminology.
• Classification-based searching (IPC, CPC, USC) to map patents by technology domain.
• Assignee and inventor searching to uncover filings from key competitors and innovators.
• Citation searching to analyse forward and backward citations.
• Similarity searching using advanced tools (e.g., ORBIT, PATSNAP) to identify closely related patent disclosures.
To deliver complete and reliable insights, we leverage leading global patent databases such as Questel Orbit, Derwent Innovations, Patseer, Patsnap, Google Patents, and Espacenet, covering 100+ jurisdictions worldwide.
We perform comprehensive sequence-based searches across both public and specialized databases to identify partial matches, and functional similarities related to your DNA, RNA, or protein sequence.
• Public Database Searches: Using NCBI BLAST and The Lens (Patent Lens), we screen globally recognized repositories to locate relevant patent.
• Advanced Database Searches (Optional): For deeper and more precise coverage, we conduct searches on the REGISTRY/DGENE (STNext), enabling highly accurate identification of biological sequences.
To ensure no relevant disclosure is missed, supplementary searches are conducted after completing both keyword-based and sequence-based searches. These include:
• Citation-based searches to trace forward and backward references, uncovering related filings, prior art linkages, and hidden dependencies that may not surface in primary searches.
• Assignee and inventor searches to capture additional filings from key players, identify continuation families, and detect sequence-related inventions associated with the same research groups or organizations.
Blast Analysis of Relevant datasets identified from Keywords based searches, sequence-based searches and supplementary searches to extract sequences with similarity ~90%* (this may vary based upon client interest). Each patent/patent application will be analyzed manually, and sequence mapping of claimed sequences will be performed with the provided sequence to find relevant claimed sequences.
We provide comprehensive report representing alignment details, percentage identity, and Relevant text etc. Additionally, for all the relevant references we provide IeB Comment which makes your analysis easier.
Tailored pricing models and quick turnaround times to meet every budget and project requirement
Pay only when you're fully satisfied: our commitment to delivering reliable, high-quality results you can trust
Comprehensive Patent and Non-Patent Literature from 100+ Countries in multiple technology areas covered across 15+ databases
Native language capabilities in 25+ countries, including CN, JP, KR, with regional database coverage for accurate native language search results
Interconvertible, easy-to-digest reports with claim element grid mapping to accelerate your decisions
Hybrid search approach Combining Artificial intelligence + Human Intelligence to deliver accurate, relevant results
Search teams in the US and India, supported by established export control compliance processes.
Multi-level firewalls and strict access protocols to ensure complete data confidentiality and compliance
Experts 300+ PhDs and SMEs with deep technical and legal expertise across ICT, Engineering, and Life Sciences disciplines
Our services are designed to support enterprises within the below mentioned industries and sectors, helping them achieve their strategic goals.
A biological sequence search involves analyzing and comparing DNA, RNA, or protein sequences to identify similarities, functional elements, and related sequences in patent databases. It plays a key role in genomics, drug discovery, molecular biology, and IP strategy by helping researchers uncover gene functions, regulatory motifs, evolutionary relationships, and potential prior art.
Most searches take 5–12 business days, depending on complexity and database coverage. If your project involves detailed patent analysis or multiple sequences, it may take slightly longer. Expedited options are available if you’re on a tight timeline.
AI tools help you uncover deeper similarities, functional links, and non-obvious homologs that traditional searches may miss. Every insight is validated by experts, so you can trust the results for your research or IP planning.
Yes—you can submit multiple sequences for batch analysis, whether for a gene family, antibody library, or multi-target project. This ensures consistent evaluation and saves your time for larger-scale research or IP programs.
A sequence search allows you to see if your sequence—or anything similar—already appears in patent literature. This helps you understand your patentability, avoid infringement issues, and strengthen your claim before filing. It ensures you enter the patent process with confidence.
Yes—you can be assured that your data is fully protected. We handle your sequences and research information with the highest level of care, following strict confidentiality protocols to safeguard your intellectual property and sensitive research.
You’ll benefit from our services whether you’re an academic researcher, work in a biotech or pharmaceutical company, or are part of a healthcare institution. We tailor our sequence search solutions to meet your specific research, patent, or innovation needs.
Getting started is simple—just fill out the inquiry form at the bottom of this page. We’ll reach out to understand your project, objectives, and timelines, then design a customized sequence search solution specifically for you.
