With significant funding from the National Institutes of Health (NIH), a researcher at The University of Texas at Arlington is investigating fundamental biological processes that lead to fertility problems in humans.
Breast cancer is one of the most common forms of cancer, and some subtypes are among the most difficult of all cancers to treat. The involvement of many different cells makes targeting such tumors challenging.
Like entrance and exit doors on a building, a cell’s outer surface has doors — channels, pumps, and transporters that selectively control what molecules enter or exit. In the immune system, T cells possess unique sets of ‘doors’, including ones that specialize in calcium ion movement. Now, researchers describe a unique mechanism for coordinating these calcium entrance and exit ‘doors’ on T cells that helps them carry out their jobs and ensure normal immune function.
The 2019 Nobel Prize in Physiology or Medicine is being awarded jointly to William G. Kaelin Jr., Sir Peter J. Ratcliffe and Gregg L. Semenza for identifying molecular machinery that regulates the activity of genes in response to varying levels of oxygen.
A few years ago, it looked like humanity was about to wipe a debilitating parasitic disease off the face of the Earth. But the long road to eradicating Guinea worm just got a whole lot longer. Faced with evidence of previously unknown routes of transmission, the World Health Organization (WHO) has quietly pushed back the target date for stamping out the disease from 2020 to 2030.
Tucked away in Tokyo’s trendiest fashion district — two floors above a pricey French patisserie, and alongside nail salons and jewellers — the clinicians at Helene Clinic are infusing people with stem cells to treat cardiovascular disease.
Fatty liver disease results when too much fat is stored in the liver, and can lead to severe inflammation, liver damage and cancer. The disease, which affects about a quarter of people in the United States, is associated with obesity, type 2 diabetes and high cholesterol. Heavy alcohol drinking can lead to fatty liver disease, but it’s been less clear why nondrinkers or people who drink moderately develop the condition.
Researchers have shown that antimicrobial-resistant infections are rapidly increasing in animals in low and middle income countries. They produced the first global of resistance rates, and identified regions where interventions are urgently needed.