Scouting Novel Therapeutic Molecule for IP Licensing - Ingenious e-Brain

Scouting Novel Therapeutic Molecule for IP Licensing

The Client

European Pharmaceutical giant.


IP head of a European pharmaceutical company approached us with a challenging task, wherein IEBS was asked to perform worldwide patent scouting for novel small pharmaceutical molecules for breast cancer therapy, originated from universities for the licensing/research collaboration purpose.

Our Solution

Considering the broad scope of the search worldwide, we broke the project into three key steps –

  • For conducting patents/patent applications searches for novel small molecules for breast cancer assigned to universities, we prepared a list and search strategies around important receptors e.g. estrogen receptors, HER-2 etc. [Results pertaining to large molecules, for example antibody, mab etc. were filtered out].
  • Results retrieved from the step 1 were subjected to important consideration with respect to successful pre-clinical reports in patent documents, research papers or undergoing clinical trial by the same assignee/inventors.
  • Finally, a detailed report was presented to client for all active patent references which claim chemical molecule with good activity report, mentioned either in patent document itself or in a research paper/conference paper/clinical trial detail. A total of 85 potential small molecules were reported.

Our Impact

The report helped IP head to select one potential small molecule in co-ordination with his R&D head. This molecule (a selective estrogen receptor modulator) has proven well in preclinical stages and survived invalidity study. Company is now planning to sponsor clinical trial study for this molecule.

our Experts